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Gene drives and malaria: how altered mosquitoes could reshape disease control

Gene drives and malaria: how altered mosquitoes could reshape disease control

Posted on April 19, 2026 By admin


Representative image of the Cas9 protein in complex with sgRNA and its target DNA. Cas9 is part of the CRISPR-Cas9 gene-editing tool. Reseach has shown that CRISPR-based gene drives can spread through small laboratory cages of mosquitoes.
| Photo Credit: Public domain

For decades, malaria control has worked by reducing the number of mosquitoes and treating infected people. As a result bed nets, indoor insecticide spraying, and effective medicines have saved millions of lives. Yet malaria remains one of the world’s deadliest infectious diseases, killing more than half a million people each year, most of them children in sub-Saharan Africa.

Anti-malaria efforts have also slowed in many regions as mosquitoes become more resistant to insecticides and the malaria parasite evolves resistance to drugs.

Published – April 20, 2026 07:30 am IST



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